Those with diabetes, especially Type-2 diabetes, are not onlystanding at the brink of heart or kidney disease, but also are at risk of developing cancers. Reports suggested the highest risk is for liver, colorectal, pancreatic, breast, endometrial, and bladder cancer. However, Dr Lalit Sharma, MBBS, MD Consultant Pathologist Lab medicine, NRL, Oncquest Labs, shares that several research studies done in the recent past bring forth an alarming link between accelerated blood cancer growth and diabetes. He says that understanding this relationship is the need of the hour.
Here's How Diabetes And Blood Cancer Are Related
"Diabetes and cancer are two of the most pressing health challenges in the present world," Dr Sharma says, pointing out that India has an "escalating diabetes epidemic, with over 74 million diagnosed cases."
The rise in blood cancer cases has also pitched India at rank 3 globally, adds the doctor. And recent researches indicate a concerning link between diabetes and blood cancer, as mentioned above.
But, why is this? "High blood glucose levels, a hallmark of diabetes, create a favourable environment for cancer cell proliferation. Elevated glucose in the bloodstream fuels cancer growth and enhances inflammation, which can further increase cancer risk," shares Dr Sharma.
Elaborating, he says, "Chronic inflammation, driven by prolonged elevated blood sugar levels, has been linked to various types of cancers, including leukaemia, lymphoma, and multiple myeloma."
Apart from this, there is also the factor of diabetes-related obesity, which contributes to cancer risk through hormonal changes, adds the doctor.
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"Excess body fat increases the production of growth factors and inflammatory cytokines, such as insulin and insulin-like growth factor-1 (IGF-1). All of this can stimulate cancer cell growth and prevent programmed cell death. This creates a tumour-friendly environment, making malignancies more likely to develop and spread," explains Dr Sharma.
The other reason why diabetes may lead to blood cancer progression is because of insulin resistance and hyperinsulinemia, which are commonly associated with diabetes.
"Higher insulin and IGF levels have been shown to promote cancer cell proliferation, making it essential for individuals with diabetes to manage their condition proactively," he cautions.
Tips To Prevent Getting Diabetes-Related Blood Cancer
As per Dr Sharma, the following are some steps you can take to avoid the dangerous situation:
- Regular monitoring of diabetes and early diagnosis of potential cancer symptoms are critical.
- Adopting a comprehensive treatment approach that includes managing blood sugar levels and addressing obesity can significantly impact cancer risk.
You should also:
- Exercise
- Limit alcohol and red meat intake
- Consume more plant-based diet like vegetables, fruits, and whole grains
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